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A CRO Built by Scientists for Scientists

Discover our comprehensive solutions for all stages of discovery and pre-clinical drug development, built by experts who truly understand your challenges.

Your Trusted Partner for High-Quality, Timely Data

icn-person“I wish my CRO was a better collaborator.”
icn-person“If I had received data from my CRO earlier, I could have made better-informed decisions.”
icn-person“I hope this time, I can count on the quality of the data.”
You probably have similar thoughts daily. We did, too. As industry scientists, we outsourced services to many Contract Research Organizations (CROs). More often than not, we were unsatisfied with data quality and timeliness, and relationships felt impersonal.
That’s why we created
DC3 Therapeutics. 

At DC3, we are a partner with the breadth of knowledge and diverse expertise to successfully work in tandem with our biotech and pharma clients - as an extension of your internal R&D teams - to provide both standard and custom services. Our team has a proven track record of designing and executing experiments to generate robust, high-quality data addressing mission-critical questions in a time-sensitive fashion, and with the utmost integrity and reliability.

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A one-stop CRO for all stages from concept to clinic

Our deep understanding of the discovery and development process is woven through every aspect of our engagement with clients. From initial request through project execution, final QC, and fulfillment of deliverables, we implement value-added, proven operational practices and communicate proactively to ensure transparency throughout all stages of a project.

As your partner, we deliver biomarker assays, companion diagnostic support, and LDTs in our CLIA-certified lab environment. 

Consulting to help align your data with IND submission requirements. 

Final-stage molecular, histological, and biochemical assessments to enable selection of the best candidate molecules. 

Quantify and qualify safety, efficacy, and tissue-level response with integrated in vitro and histology support. 

High-content screens and custom target-based assays refined into tailored identification and characterization platforms to meet your unique needs.

Target validation and screening campaigns executed using flexible tools for genome editing, gene expression, and functional biology.

First-in-Human Phase

Central Lab Support 

As your partner, we deliver biomarker assays, companion diagnostic support and LDTs in our CLIA-certified lab environment. 

IND Enablement Phase

Regulatory-Ready POC 

We support GLP-like documentation, custom LDT development and digital pathology to align your data with IND submission needs. 

Candidate Development

Characterize. Validate. Advance. 

Final-stage molecular, histological and biochemical assessments to support selection of the best candidate molecules. 

Preclinical Development

Define the Risk 

Quantify and qualify safety, efficacy and tissue-level response with integrated in vitro and histology support. 

Optimization

Accelerate Lead Optimization with Smart Assays 

From high-content screens to custom target-based assays, we tailor identification and characterization platforms to your unique needs.

Discovery

We Know Where to Start 

Empower target validation and screening campaigns with flexible tools for genome editing, gene expression and functional biology.

Our Extensive Suite of Services

  • Cell and Molecular Biology
  • Biochemical, Biophysical, and Cell-based Assays
  • Protein Chemistry and Biochemistry
  • IHC and Spatial Biology
  • Clinical Chemistry
  • In Vitro and In Vivo Consulting and Program Management 

Tailored solutions that accelerate discovery

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Discovery

  • Target identification
  • Target validation
  • Mechanism of action studies

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Pre-clinical / IND-enabling studies

  • Toxicology
  • Pharmacokinetics
  • In vitro ADMET
  • In vivo studies

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Clinical studies

  • Biomarker discovery

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Diagnostics

  • CDx assay development

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Discovery

  • Target identification
  • Target validation
  • Mechanism of action studies

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Pre-clinical / IND-enabling studies

  • Toxicology
  • Pharmacokinetics
  • In vitro ADMET
  • In vivo studies

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Clinical studies

  • Biomarker discovery

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Diagnostics

  • CDx assay development

Long-term partnerships that drive results

  • Success in discovery and development
  • Translational not transactional partnerships
  • Real-time, actionable insights for efficient and cost-effective decision-making
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CymaBay Therapeutics recently worked with DC3 on a project which required generation of novel assays for small molecule therapeutics. The depth of scientific background knowledge at DC3 as well as the highly collaborative assay design process allowed the project to be completed on time and on budget with highly satisfactory results. The willingness of DC3 staff to adapt experimental design and workflow to the client’s needs was critical to the effort. DC3 has an expansive array of assays, analytical methods and other capabilities for drug development that can augment or expand the scope of what the client can perform in house. In our case, they provided expertise, hands-on experience and quality control to quickly achieve the objectives of our project.
 
Jeffrey D. Johnson, PhD
Drug Discovery Consultant
CymaBay Therapeutics

Our customers

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Contact us for a free consultation on any of your research needs!